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Structure of the N-terminal RNA-binding domain of the SARS CoV nucleocapsid protein

Authors :
Huang, Quilong ;
Yu, Liping
Petros, Andrew M.
Gunasekara, Angelo
Liu, Zhihong
Xu, Nan
Hajduk, Philip
Mack, Jamey
Fesik, Stephen W.
Olejniczak, Edward T.
Source :
Biochemistry. May 25, 2004, Vol. 43 Issue 20, 6059-6063
Publication Year :
2004

Abstract

The three-dimensional structure of the N-terminal domain of the severe acute respiratory syndrome (SARS) coronavirus (CoV) nucleocapsid protein is presented. By using a nuclear magnetic resonance (NMR) spectroscopy, the low molecular weight compounds that bind to the RNA-binding face of the protein is discussed.

Details

Language :
English
ISSN :
00062960
Volume :
43
Issue :
20
Database :
Gale General OneFile
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.121784332