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Reaction of Pseudomonas fluorescens Kynureninase with Beta-Benzoyl-L-alanine: detection of a new reaction intermediate and a change in rate-determinig step

Authors :
Gawandi, Vijay B.
Liskey, Diane
Lima, Santiago
Phillips, Robert S.
Source :
Biochemistry. March 23, 2004, Vol. 43 Issue 11, 3230-3237
Publication Year :
2004

Abstract

The pre-steady-state kinetics of the reaction of Beta-benzoyl-L-alanine was investigated by rapid scanning stopped-flow spectrophotometry. The spectra show the formation of a quinonoid intermediate and also support the formation of benzoate as the rate-determining step.

Details

Language :
English
ISSN :
00062960
Volume :
43
Issue :
11
Database :
Gale General OneFile
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.121828520