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Evidence of endothelial dysfunction in preeclampsia: decreased endothelial nitric oxide synthase expression is associated with increased cell permeability in endothelial cells from preeclampsia
- Source :
- American Journal of Obstetrics and Gynecology. March, 2004, Vol. 190 Issue 3, p817, 824 p.
- Publication Year :
- 2004
-
Abstract
- The endothelial nitric oxide synthase (eNOs) expression in endothelial cells from normal and preeclamptic pregnancies are determined to investigate the potential role of eNOs in regulating endothelial permeability in preeclampsia. The messenger RNA and eNOs expression are decreased in endothelial cells from preeclampsia and the inhibition of eNOs activity has increased the endothelial permeability.
- Subjects :
- Preeclampsia -- Research
Interleukin-8 -- Research
Nitric oxide -- Research
Health
Subjects
Details
- Language :
- English
- ISSN :
- 00029378
- Volume :
- 190
- Issue :
- 3
- Database :
- Gale General OneFile
- Journal :
- American Journal of Obstetrics and Gynecology
- Publication Type :
- Periodical
- Accession number :
- edsgcl.121847405