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Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways
- Source :
- Cell. April 2, 2004, Vol. 117 Issue 1, 69-81
- Publication Year :
- 2004
-
Abstract
- Dicer-1 and Dicer-2 facilitate the assembly of siRISC (RNA-induced silencing complex). But genetic analysis has demonstrated that Dcr-1 but not Dcr-2 is required for gene silencing by miRNAs.
Details
- Language :
- English
- ISSN :
- 00928674
- Volume :
- 117
- Issue :
- 1
- Database :
- Gale General OneFile
- Journal :
- Cell
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.122300955