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In vitro prion protein conversion in detergent-solubilized membranes
- Source :
- Biochemistry. March 9, 2004, Vol. 43 Issue 9, 2613-2621
- Publication Year :
- 2004
-
Abstract
- The ability of enriched membrane subsets and detergent-solubilized membrane preparations were investigated to support PrPres amplification. The observation that detergent-solubilized preparations containing PrPc but lacking membranes supported the PrPres amplification, which indicated that intact lipid membranes were not essential for efficient PrP conversion.
Details
- Language :
- English
- ISSN :
- 00062960
- Volume :
- 43
- Issue :
- 9
- Database :
- Gale General OneFile
- Journal :
- Biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.122868423