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Insulin-like growth factor I gene promoter polymorphism, collagen type II alpha 1 (COL2A1) gene, and the prevalence of radiographic osteoarthritis: the Rotterdam study

Authors :
Zhai, G.
Rivadeneira, F.
Houwing-Duistermaat, J.J.
Meulenbelt, I.
Bijkerk, C.
Hofman, A.
Meurs, J.B.J. van
Uitterlinden, A. G.
Pols, H.A.P.
Slagboom, P.E.
Duijn, C.M. van
Source :
Annals of the Rheumatic Diseases. May, 2004, Vol. 63 Issue 5, p544, 5 p.
Publication Year :
2004

Abstract

The main aim of this study is to identify the role of insulin-like growth factor I in the prevalence of radiographic osteoarthritis. Insulin-like growth factor I is a polypeptide mediator with a potent anabolic impact on cartilage homeostasis.

Details

Language :
English
ISSN :
00034967
Volume :
63
Issue :
5
Database :
Gale General OneFile
Journal :
Annals of the Rheumatic Diseases
Publication Type :
Periodical
Accession number :
edsgcl.123149632