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Secondary structure of DNA is recognized by slightly cross-linked cationic hydrogel

Authors :
Sergeyev, Vladimir G.
Novoskoltseva, Olga A.
Pyshkina, Olga A.
Zinchenko, Anatoly A.
Rogacheva, Valentina B.
Zezin, Alexander B.
Yoshikawa, Kenichi
Kabanov, Victor A.
Source :
Journal of the American Chemical Society. Sept 25, 2002, Vol. 124 Issue 38, 11324-11333
Publication Year :
2002

Abstract

Interaction of salmon sperm DNA (300-500 bp) and ultrahigh molecular mass DNA (166 kbp) from bacteriophage T4dC with linear poly(N-diallyl-N-dimethylammonium chloride) (PDADMAC) and slightly cross-linked (#) PDADMAC (#PDADMAC) hydrogel in water are studied. It is found that the linear polycation induced compaction of either native (double-stranded) or denatured (single-stranded) DNA by forming PDADMAC-DNA interpolyelectrolyte complexes (IPEC)s.

Details

Language :
English
ISSN :
00027863
Volume :
124
Issue :
38
Database :
Gale General OneFile
Journal :
Journal of the American Chemical Society
Publication Type :
Academic Journal
Accession number :
edsgcl.123650731