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The HPV16 E7 viral oncoprotein self-assemblies into defined spherical oligomers
- Source :
- Biochemistry. March 30, 2004, Vol. 43 Issue 12, 3310-3317
- Publication Year :
- 2004
-
Abstract
- The ability of HPV16 E7, a major transforming oncoprotein in papillomavirus, to self-assemble in the absence of zinc into defined spherical oligomer is explained. The conformational characterization of these structures is done by means of electron microscopy, dynamic light scattering and spectroscopic techniques like circular dichroism and fluorescence.
Details
- Language :
- English
- ISSN :
- 00062960
- Volume :
- 43
- Issue :
- 12
- Database :
- Gale General OneFile
- Journal :
- Biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.123897225