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Highly efficient and enantioselective cyclization of aromatic imines via imines via directed C-H bond activation
- Source :
- Journal of the American Chemical Society. June 16, 2004, Vol. 126 Issue 23, 7192-7193
- Publication Year :
- 2004
-
Abstract
- A highly enantioselective and efficient method is developed for the intramolecular imine-directed C-H/olefin coupling reaction using chiral phosphoramidite ligands. The exceptional rates and enantioselectives observed using the phosphoramidite ligands may be due to their unique binding properties, which include reduced sigma donation to rhodium and enhanced pie acceptor ability compared to phosphines.
Details
- Language :
- English
- ISSN :
- 00027863
- Volume :
- 126
- Issue :
- 23
- Database :
- Gale General OneFile
- Journal :
- Journal of the American Chemical Society
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.124044978