Pharmacokinetics of indinavir/ritonavir (800/100mg) in combination with efavirenz ({600mg) in HIV-1-infected subjects

Authors :: Boyd, Mark A.
Aarnoutse, Rob E.
Ruxrungtham, Kiat
Stek, Michael, Jr
Heeswijk, Rolf P. G. van
Lange, Joep M. A.
Cooper, David A.
Phanuphak, Praphan
Burger, David M.
Source :: Journal of Acquired Immune Deficiency Syndromes (1999). Oct 1, 2003, Vol. 34 Issue 2, p134, 6 p.
Publication Year :: 2003
Abstract: Efavirenz (600mg) is added to indinavir/ritonavir (800/100mg) results in significant decreases in indinavir levels in healthy volunteers. The combination of indinavir/ritonavir (800/100mg) bid and efavirenz at 600mg results in adequate minimum concentrations of both indinavir and efavirenz for treating native patients.

Subjects :: Patients -- Research
Indinavir -- Research
Pharmacokinetics -- Research
Health

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