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Real time measurement of in vitro peptide binding to soluble HLA-A*0201 by fluorescence polarization
- Source :
- Biochemistry. Nov 23, 2004, Vol. 43 Issue 46, p14852, 12 p.
- Publication Year :
- 2004
-
Abstract
- The development of a sensitive biochemical assay that relies upon fluorescence polarization is reported to indicate peptide interactions with recombinant soluble human leukocyte antigens (HLA) proteins. Testing of the A*0201-specific peptides with 48 additional class I molecules demonstrates that the unique peptide binding behavior of individual HLA molecules is maintained in the assay.
Details
- Language :
- English
- ISSN :
- 00062960
- Volume :
- 43
- Issue :
- 46
- Database :
- Gale General OneFile
- Journal :
- Biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.126835689