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Studies on the inactivation of bovine liver enoyl-CoA hydratase by(Methylenecyclopropyl) formyl-CoA: Elucidation of the inactivation mechanism and identification of cysteine-114 as the entrapped nucleophile
- Source :
- Journal of the American Chemical Society. Oct 20, 2001, Vol. 123 Issue 40, p9749, 11 p.
- Publication Year :
- 2001
-
Abstract
- Inhibitory properties of (methylene cyclopropyl) formyl-CoA (MCPF-CoA), (methylenecyclopropyl) glycine against enoyl-CoA hydratase (ECH) were studied. This helps in selection of inhibitors to control fatty acid metabolism.
- Subjects :
- Glycine -- Chemical properties
Methylene blue -- Chemical properties
Chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 00027863
- Volume :
- 123
- Issue :
- 40
- Database :
- Gale General OneFile
- Journal :
- Journal of the American Chemical Society
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.127584765