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Engineering a hybrid sugar biosynthetic pathway: production of L-rhamnose and its implication on dihydrostreptose biosynthesis
- Source :
- Journal of the American Chemical Society. Dec 13, 2000, Vol. 122 Issue 49, p12397, 2 p.
- Publication Year :
- 2000
-
Abstract
- The Strptomyces venezuelae strains containing selected genes from the L-dihydrostreptose pathway are constructed and the biosynthetic implications obtained for the dihydrostreptose pathway are reported. The versatility of the glycosyltransferase on substrate selection highlights its potential as a catalyst in the construction of new macrolides carrying a broad range of modified sugars.
- Subjects :
- Transferases -- Research
Biosynthesis -- Research
Chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 00027863
- Volume :
- 122
- Issue :
- 49
- Database :
- Gale General OneFile
- Journal :
- Journal of the American Chemical Society
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.127606100