Full stereochemical assignment and synthesis of the potent anthelmintic pyrrolobenzoxazine natural product CJ-12662

Authors :: Didier, Charles
Critcher, Douglas J.
Walshe, Nigel D.
Kojima, Yasuhiro
Yamauchi, Yuji
Barrett, Anthony G. M.
Source :: Journal of Organic Chemistry. Nov 12, 2004, Vol. 69 Issue 23, p7875, 5 p.
Publication Year :: 2004
Abstract: Structure of the unusual anthelmintic pyrrolobenzoxazine terpenoid natural product CJ-12662 was confirmed by X-ray crystallography and partial synthesis from 2-chloronitrobenzene. The pyrrolobenzoxazine moiety was synthesized using dye-sensitized photooxygenation of a tryptophan derivative.

Subjects :: Benzene -- Chemical properties
X-ray crystallography -- Research
Chemical synthesis -- Research
Pyrrole -- Chemical properties
Anthelmintics -- Chemical properties
Biological sciences
Chemistry

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