Novel bromotyrosine derivatives that inhibit growth of the fish pathogenic bacterium Aeromonas hydrophila, from a marine sponge Hexadella sp

A search for biologically active compounds found that the hydrophilic extract of a marine sponge Hexadella sp. collected in southern Japan exhibited moderate antibacterial activity against the bacterium Aeromonas hydrophila, which causes hemorrhagic septicemia in fish. Their structures were elucidated on the basis of spectral and chemical methods and they exhibited moderate antibacterial activity against the fish pathogenic bacterium Aeromonas hydrophila.