Human glucocorticoid receptor alpha transcript splice variants with exon 2 deletions: Evidence for tissue- and cell type-specific functions

Four novel glucocorticoid receptor (hGR) alpha transcripts that have various deletions of exon 2 sequences are identified. Among these hGRalpha splice variants, three of them, 1A1/E2dist hGRalpha, 1A2/E2prox hGRalpha and 1A3/E3 hGRalpha, arise from the hGR 1 A promoter, while 1B/E3 hGRalpha comes from the hGR 1 B promoter.