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On the origin of the thermostabilization of proteins induced by sodium phosphate
- Source :
- Journal of the American Chemical Society. July 13, 2005, Vol. 127 Issue 27, 9690-9691
- Publication Year :
- 2005
-
Abstract
- The relationship between the intrinsic thermal stability of the different mutants and their sensitivity to phosphate-induced thermostabilization is demonstrated using site-directed mutagenesis of surface residues. The clear difference between the effect of phosphate and chloride ions demonstrates that the observed stabilization is not simply a result of changes in ionic strength.
Details
- Language :
- English
- ISSN :
- 00027863
- Volume :
- 127
- Issue :
- 27
- Database :
- Gale General OneFile
- Journal :
- Journal of the American Chemical Society
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.135259951