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Identification of potent and selective RNA antagonists of the IFN-gamma-inducible CXCL10 chemokine
- Source :
- Biochemistry. June 14, 2005, Vol. 44 Issue 23, 8449-8460
- Publication Year :
- 2005
-
Abstract
- The isolation of a series of nuclease-resistant RNA aptamers that act to antagonize human CXCL10 function in a number of in vitro and cell-based assays is reported. A further aptamer was identified that antagonized human and the mouse CXCL10.
Details
- Language :
- English
- ISSN :
- 00062960
- Volume :
- 44
- Issue :
- 23
- Database :
- Gale General OneFile
- Journal :
- Biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.135439656