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Mechanisms of NO release by N(super 1)-nitrosomelatonin: Nucleophilic attack versus reducing pathways

Authors :
Biase, Pablo M. De
Turjanski, Adrian G.
Estrin, Dario A.
Doctorovich, Fabio
Source :
Journal of Organic Chemistry. July 22, 2005, Vol. 70 Issue 15, p5790, 9 p.
Publication Year :
2005

Abstract

A study of the denitrosation mechanism of N(super 1)-nitrosomelatonin (NOMe1) as a model for N(super 1)-nitrosoindoles is presented. The results revealed that NOMe1 slowly decomposes spontaneously in aqueous solution, generating melatonin as the main organic product.

Subjects

Subjects :
Melatonin -- Chemical properties
Nitric oxide -- Chemical properties
Nucleophilic reactions -- Research
Biological sciences
Chemistry

Details

Language :
English
ISSN :
00223263
Volume :
70
Issue :
15
Database :
Gale General OneFile
Journal :
Journal of Organic Chemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.135488375

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