Substrate discrimination by cholapod anion receptors: Geometric effects and the affinity-selectivity principle

Cholapod anion receptors are capable of high affinities while retaining compatibility with nonpolar organic media. Among the 13 receptors studied, the structures include between three and six H-bond donors sited in urea, thiourea, sulfonamide, carbamate, trofluoroacetamide and isophthalamide binding units.