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Structure, flexibility, and repair of two different orientations of the same alkyl interstrand DNA cross-links
- Source :
- Biochemistry. May 10, 2005, Vol. 44 Issue 18, 6764-6775
- Publication Year :
- 2005
-
Abstract
- A study characterizes the repair, structure, and flexibility of DNA that contains N4C-ethyl-N4C interstand DNA cross-link in two different orientations. A combination of (super 1)H nuclear magnetic resonance (NMR), restrained molecular dynamics simulations, and atomic force microscopy (AFM) was used to examine the structure and flexibility of DNA containing these cross-links.
Details
- Language :
- English
- ISSN :
- 00062960
- Volume :
- 44
- Issue :
- 18
- Database :
- Gale General OneFile
- Journal :
- Biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.135773769