Protein kinase C isozymes epsilon and alpha in murine erythroleukemia cells

Authors :: Powell, C. T.
Leng, L.
Dong, L.
Busquets, X.
O'Driscoll, K.
Marks, P. A.
Rifkind, R. A.
Source :: Proceedings of the National Academy of Sciences of the United States. Jan 1, 1992, Vol. 89 Issue 1, p147, 5 p.
Publication Year :: 1992
Abstract: Murine erythroleukemia cells contained the protein kinase C (PKC) epsilon and alpha isoenzymes but no PKC beta isoenzymes. Hydroxylapatite column chromatography separated the different Ca2+-dependent isoenzymes and showed major and minor peaks of PKC activity. Immunoblot analysis using antibodies specific for PKCalpha and PCKepsilon revealed that the the minor peak contained PKCepsilon and not PKCbeta as previously identified while the major peak was noted to be predominated by PKCalpha.

Subjects :: Protein kinases -- Research
Isoenzymes -- Research
Erythrocytes -- Analysis
Erythrocyte disorders -- Research
Science and technology

ISSN :: 00278424
Volume :: 89
Issue :: 1
Database :: Gale General OneFile
Journal :: Proceedings of the National Academy of Sciences of the United States
Publication Type :: Academic Journal
Accession number :: edsgcl.13595030

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