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Two members of a widely expressed subfamily of hormone-stimulated adenylyl cyclases

Authors :
Premont, Richard T.
Chen, Jianqiang
Hai-Wen Ma
Ponnapalli, Madhavi
Iyengar, Ravi
Source :
Proceedings of the National Academy of Sciences of the United States. Oct 15, 1992, Vol. 89 Issue 20, p9809, 5 p.
Publication Year :
1992

Abstract

A study was done on two members of a widely expressed subfamily of hormone-stimulated adenylyl cyclases. It was shown that the cDNA encoding a hormone- and guanine nucleotide-stimulated adenylyl cyclase is stimulated by forskolin but not by betagamma subunits of guanine nucleotide-binding proteins. Another form was cloned and together with the type 5 enzyme define one distinct subfamily of mammalian adenylyl cyclases.

Details

ISSN :
00278424
Volume :
89
Issue :
20
Database :
Gale General OneFile
Journal :
Proceedings of the National Academy of Sciences of the United States
Publication Type :
Academic Journal
Accession number :
edsgcl.13849704