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Recognition of a guanine-cytosine base pair by 8-oxoadenine
- Source :
- Biochemistry. July 28, 1992, Vol. 31 Issue 29, p6788, 6 p.
- Publication Year :
- 1992
-
Abstract
- The interaction of two oligodeoxyribonucleotides, I(A) and II(A), with the duplex deoxyribonucleotide III-IV(Y-Z) was studied. The results of continuous variation experiments, melting experiments and circular dichroism spectroscopy show that I(A) and II(A) each form triplexes with III-IV(Y-Z) at neutral and basic pH. Moreover, it appears that 8-oxoadenine residue in the two oligodeoxyribonucleotides interacts in a specific manner with G-C base pairs of the duplex.
Details
- ISSN :
- 00062960
- Volume :
- 31
- Issue :
- 29
- Database :
- Gale General OneFile
- Journal :
- Biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.13897100