Attenuation by contextual cues of retroactive interference of a conditional discrimination in rats

We investigated the effect of associating unique contextual cues with an interpolated learning task on retroactive interference in long-term memory. Rats were originally trained in a two-bar operant chamber with an auditory conditional discrimination stimulus. During interpolated learning, which occurred in either the original or a new context, some rats were trained on a probability learning task that did not include the auditory stimuli present during original learning. Subsequent retraining on the original conditional discrimination task in the original context showed that (1) significant retroactive interference occurs in rats, and (2) the presence of unique contextual cues during interpolated learning significantly reduces this interference. These results extend the conditions under which the susceptibility to retroactive interference can be altered by contextual cues.