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The molecular clock mediates leptin-regulated bone formation
- Source :
- Cell. Sept 9, 2005, Vol. 122 Issue 5, p803, 13 p.
- Publication Year :
- 2005
-
Abstract
- A study demonstrates that clock genes in osteoblasts mediate the leptin-dependant sympathetic inhibition of bone formation. The regulation of bone-formation by leptin through two antagonistic pathways is reminiscent of the dual mechanism that leptin uses to regulate bone resorption.
Details
- Language :
- English
- ISSN :
- 00928674
- Volume :
- 122
- Issue :
- 5
- Database :
- Gale General OneFile
- Journal :
- Cell
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.140085644