Molecular classification of patients with unexplained hamartomatous and hyperplastic polyposis

Authors :: Sweet, Kevin
Bridgeman, Scott
Heinz, John
Willis, Joseph
Martin, Cossette
Pilarski, Robert
Eng, Charis
Xiao-Ping Zhou
Patocs, Attila
Lehtonen, Rainer
Aaltonen, Lauri A.
Gallione, Carol
Khoo, Sok Kean
Prior, Thomas W.
Marchuk, Douglas A.
Sawada, Takeshi
Alhopuro, Pia
Frebourg, Thierry
Teh, Bin Tean
Source :: JAMA, The Journal of the American Medical Association. Nov 16, 2005, Vol. 294 Issue 19, p2465, 9 p.
Publication Year :: 2005
Abstract: Patients with unexplained hamartomatous or hyperplastic/mixed polyposis were systematically classified by extensive molecular analysis in the context of central rereview of histopathology results. Systematic molecular classification of 49 patients with unexplained hamartomatous or hyperplastic polyposis uncovered a potential novel susceptibility gene, ENG, for juvenile polyposis.

Subjects :: Peutz-Jeghers syndrome -- Diagnosis
Peutz-Jeghers syndrome -- Comparative analysis
Intestinal polyps -- Diagnosis
Intestinal polyps -- Comparative analysis

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