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Dipyridamole bioavailability in subjects with reduced gastric acidity

Authors :
Derendorf, Hartmut
VanderMaelen, Cam P.
Brickl, Rolf-Stefan
MacGregor, Tom R.
Eisert, Wolfgang
Source :
Journal of Clinical Pharmacology. July 2005, Vol. 45 Issue 7, p845, 6 p.
Publication Year :
2005

Abstract

Dipyridamole (DP) is an antiplatelet agent that shows decreased oral bioavailability with increased gastric pH that occurs with commonly prescribed antacids. An extended-release (ER) formulation of DP that employs tartaric [...]

Subjects

Subjects :
Aged -- Health aspects -- Research
Stroke (Disease) -- Prevention -- Drug therapy -- Research
Gastric acid -- Drug therapy -- Research -- Health aspects
Dipyridamole -- Dosage and administration -- Research
Health
Drug therapy
Prevention
Research
Dosage and administration
Health aspects

Details

Language :
English
ISSN :
00912700
Volume :
45
Issue :
7
Database :
Gale General OneFile
Journal :
Journal of Clinical Pharmacology
Publication Type :
Academic Journal
Accession number :
edsgcl.140794885

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Authors Abstract Subjects Details