Water-soluble calix[4]resorcarenes as enantioselective NMR shift reagents for aromatic compounds

Authors :: Dignam, Catherine F.
Zopf, Jason J.
Richards, Christopher J.
Wenzel, Thomas J.
Source :: Journal of Organic Chemistry. Sept 30, 2005, Vol. 70 Issue 20, p8071, 8 p.
Publication Year :: 2005
Abstract: A tetra L-prolinylmethyl derivative of a tetra-sulfonated calix[4]resorcarenes is an effective chiral NMR solvating agent for water-soluble compounds with phenyl, pyridyl, bicyclic aromatic, or indole rings. The effectiveness of a calix[4]resorcarenes prepared from N-methyl-L-alanine as a chiral NMR discriminating agent is compared to the L-prolinylmethyl derivative. for other types of water-soluble organic salts is described.

Subjects :: Nuclear magnetic resonance spectroscopy -- Usage
Aromatic compounds -- Chemical properties
Aromatic compounds -- Structure
Calixarenes -- Chemical properties
Calixarenes -- Structure
Methyl groups -- Chemical properties
Methyl groups -- Structure
Biological sciences
Chemistry

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