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Modular total synthesis of lamellarin D

Authors :
Pla, Daniel
Marchal, Antonio
Olsen, Christian A.
Albericio, Fernando
Alvarez, Mercedes
Source :
Journal of Organic Chemistry. Sept 30, 2005, Vol. 70 Issue 20, p8231, 4 p.
Publication Year :
2005

Abstract

A modular total synthesis of lamellarin D, a marine alkaloid with potent cytotoxic as well as topoisomerase I inhibition properties, are accomplished. A sequential and regioselective bromination/Suzuki cross-coupling procedure was applied for the introduction of aryl groups.

Details

Language :
English
ISSN :
00223263
Volume :
70
Issue :
20
Database :
Gale General OneFile
Journal :
Journal of Organic Chemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.141794093