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Bacterial and retroviral superantigens share a common binding region on class II MHC antigens
- Source :
- Nature. July 8, 1993, Vol. 364 Issue 6433, p152, 3 p.
- Publication Year :
- 1993
-
Abstract
- Synthetic peptides are used to detect a site on the mouse mammary tumour virus (MMTV)-1 superantigen that binds to class II major histocompatibility complex (MHC) antigens, which is surrounded by amino-acid residues 76-119 of the MMTV-1 superantigens. Experiments involving direct binding and competition reveal that the MMTV superantigen and Staphylococcal enterotoxin A (SEA) bind to atleast one common region on class II-MHC antigens.
Details
- ISSN :
- 00280836
- Volume :
- 364
- Issue :
- 6433
- Database :
- Gale General OneFile
- Journal :
- Nature
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.14216350