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Effect of finite size on cooperativity and rates of protein folding

Authors :
Kouza, Maksim
Mai Suan Li
O'Brien, Edward P., Jr.
Chin-Kun Hu
Thirumalai, D.
Source :
Journal of Physical Chemistry A. Jan 19, 2006, Vol. 110 Issue 2, p671, 6 p.
Publication Year :
2006

Abstract

The dependence of cooperativity of the thermal denaturation transition and folding rates of globular proteins on the number of amino acid residues, N. The results show that the folding free energy barrier scales only sublinearly with N.

Subjects

Subjects :
Protein folding -- Research
Globular proteins -- Chemical properties
Amino acids -- Chemical properties
Chemicals, plastics and rubber industries

Details

Language :
English
ISSN :
10895639
Volume :
110
Issue :
2
Database :
Gale General OneFile
Journal :
Journal of Physical Chemistry A
Publication Type :
Academic Journal
Accession number :
edsgcl.142527851

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