Engineering of Phenylacetaldehyde reductase for efficient substrate conversion in concentrated 2-Propanol

Authors :: Makino, Yoshihide
Inoue, Kousuke
Dairi, Tohru
Itoh, Nobuya
Source :: Applied and Environmental Microbiology. August, 2005, Vol. 71 Issue 8, 4713-4720
Publication Year :: 2005
Abstract: Phenylacetaldehyde reductase (PAR) is suitable for the conversion of various aryl ketones and 2-alkanones to corresponding chiral alcohols. 2-Propanal acts as a substrate solvent and hydrogen donor of coupled cofactor regeneration during the conversion of substrate catalyzed by PAR.

Subjects :: Propanols -- Chemical properties
Aromatic compounds -- Chemical properties
Ketones -- Chemical properties
Biological sciences

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