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The calculated genetic barrier for antiretroviral drug resistance substitutions is largely similar for different HIV-1 subtypes

Authors :
van de Vijver, David
Wensing, Annemarie M.J.
Angarano, Gioacchino
Asjo, Birgitta
Balotta, Claudia
De Luca, Andrea
Derdelinckx, Inge
Maljkovic, Irina
de Mendoza, Carmen
Meyer, Laurence
Nielsen, Claus
de Coul, Eline L.M. Op
Ormaasen, Vidar
Paraskevis, Dimitris
Perrin, Luc
Puchhammer-Stockl, Elisabeth
Ruiz, Lidia
Salminen, Mika
Schmit, Jean-Claude
Schneider, Francois
Schuurman, Rob
Soriano, Vincent
Stanczak, Grzegorz
Stanojevic, Maja
Vandamme, Anne-Mieke
Laethem, Kristel Van
Violin, Michela
Wilbe, Karin
Yerly, Sabine
Zazzi, Maurizio
Boucher, Charles A.B.X
Grossman, Zehava
Hamouda, Osamah
Hulzokis, Angelos
Hemmer, Robert
Hoepelman, Andy
Horban, Andrzej
Korn, Klaus
Kucherer, Claudia
Leitner, Thomas
Loveday, Clive
MacRae, Eilidh
Source :
Journal of Acquired Immune Deficiency Syndromes (1999). March 1, 2006, Vol. 41 Issue 3, p352, 9 p.
Publication Year :
2006

Abstract

The genetic barrier between subtypes are compared using some 2000 HIV-1 sequences (>600 of non-B subtype) isolated from anti-retroviral-naive patients in Europe. Based on the calculated genetic barrier, the rate of drug resistance development may be similar for different HIV-1 subtypes.

Subjects

Subjects :
HIV patients -- Care and treatment
HIV patients -- Genetic aspects
HIV infection -- Care and treatment
HIV infection -- Genetic aspects
Drug resistance -- Genetic aspects
Health

Details

Language :
English
ISSN :
15254135
Volume :
41
Issue :
3
Database :
Gale General OneFile
Journal :
Journal of Acquired Immune Deficiency Syndromes (1999)
Publication Type :
Academic Journal
Accession number :
edsgcl.145591241

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Authors Abstract Subjects Details