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Triplex formation by an oligonucleotide containing N4-(3-acetamidopropyl)cytosine
- Source :
- Journal of Organic Chemistry. Sept 10, 1993, Vol. 58 Issue 19, p5048, 2 p.
- Publication Year :
- 1993
-
Abstract
- The creation of C+.G.C and T.A.T base triads result in the reaction between oligodeoxyribopyrimidines and the homopurine strand of an oligodeoxyribopurine.oligodeoxyribopyrimidine duplex. An oligodeoxyribopyrimidine with N4-(3-acetamidopropyl)cytosine and the duplex reveal the creation of a triplex. The C.G base pair of the duplex reacts with the side chains of N4-(3-aminopropyl)C or N4-(3-acetamidopropyl)C in a particular fashion. The base reacts with C.G and T.A base pairs due to the shape-selective identification in 4-(3-benzamidophenyl)imidazole and not due to particular hydrogen-bonding reactions.
- Subjects :
- Cytosine -- Research
Nucleotide sequence -- Analysis
Biological sciences
Chemistry
Subjects
Details
- ISSN :
- 00223263
- Volume :
- 58
- Issue :
- 19
- Database :
- Gale General OneFile
- Journal :
- Journal of Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.14569030