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Activation and differentiation requirements of primary T cells in vitro
- Source :
- Proceedings of the National Academy of Sciences of the United States. Oct 1, 1993, Vol. 90 Issue 19, p8987, 5 p.
- Publication Year :
- 1993
-
Abstract
- Activation of primary T cells, which results in a yield of interleukin 2 (IL-2), necessitates the presence of two signals. T-cell antigen receptor stimulus and presence of IL-2 minimal are prerequisites for the feasibility of differentiation of native cells into primed ones. Autocrine nature of native T cells affects their proliferation and differentiation.
Details
- ISSN :
- 00278424
- Volume :
- 90
- Issue :
- 19
- Database :
- Gale General OneFile
- Journal :
- Proceedings of the National Academy of Sciences of the United States
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.14638444