Effects of high glucose concentrations and epalrestat on sorbitol and myo-inositol metabolism in cultured rabbit aortic smooth muscle cells

Authors :: Sakakibara, Fumihiko
Hotta, Nigishi
Koh, Naoki
Sakamoto, Nobuo
Source :: Diabetes. November 1993, Vol. 42 Issue 11, p1594, 7 p.
Publication Year :: 1993
Abstract: To clarify the relationship between abnormality of sorbitol and/or myo-inositol metabolism caused by hyperglycemia and diabetic macroangiopathy, we investigated the effects of high glucose concentrations and epalrestat, an aldose reductase [...]

Subjects :: Aldose reductase -- Physiological aspects
Inositol -- Physiological aspects
Hyperglycemia -- Complications and side effects
Atherosclerosis -- Causes of -- Complications and side effects
Health
Complications and side effects
Physiological aspects
Causes of

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