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Linear aglycones are the substrates for glycosyltransferase DesVll in methymycin biosynthesis: Analysis and implications
- Source :
- Journal of the American Chemical Society. May 3, 2006, Vol. 128 Issue 17, 5606-5607
- Publication Year :
- 2006
-
Abstract
- The aglycone is biosynthesized by the sequential condensation of acyl thioesters catalyzed polyketide synthases (PKS). The results show that the linear polyketide chain 8 can serve as a chemically competent substrate for macrolide glycosyltransferase discovery of an auxiliary protein (DesVII).
- Subjects :
- Polyketides -- Chemical properties
Glycogen -- Synthesis
Protein research
Chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 00027863
- Volume :
- 128
- Issue :
- 17
- Database :
- Gale General OneFile
- Journal :
- Journal of the American Chemical Society
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.146879586