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Molecular mechanism of the Thermus thermophilus ADP- ribose pyrophosphatase from mutational and kinetic studies

Authors :
Ooga, Takushi
Yoshiba, Sachico
Nakagawa, Norika
Kuramitsu, Seiki
Masui, Ryoji
Source :
Biochemistry. July 5, 2005, Vol. 44 Issue 26, 9320-9329
Publication Year :
2005

Abstract

ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose 5' -phosphate. The results state that interactions responsible for the substrate recognition are located at the terminal moieties of the substrate.

Details

Language :
English
ISSN :
00062960
Volume :
44
Issue :
26
Database :
Gale General OneFile
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
edsgcl.147186660