(IPr)Pd(acac)Cl: An early synthesized, efficient and versatile precatalyst for C-N and C-C bond formation

Authors :: Marion, Nicolas
Ecarnot, Elise C.
Navarro, Oscar
Amoroso, Dino
Bell, Andrew
Nolan, Steven P.
Source :: Journal of Organic Chemistry. May 12, 2006, Vol. 71 Issue 10, p3816, 6 p.
Publication Year :: 2006
Abstract: A new synthetic route leading to a PdH precatalyst in one step from a stable NHC salt and the commercially available Pd(acac)2 is described. The resulting complex, (IPr)-Pd(acac)Cl has shown excellent catalytic activity in the Buchwald Hartwig and the alpha-ketone arylation reactions using aryl chlorides under milk reaction conditions.

Subjects :: Acetone -- Chemical properties
Acetylene -- Chemical properties
Palladium catalysts -- Chemical properties
Imidazole -- Chemical properties
Arylation -- Analysis
Biological sciences
Chemistry

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