Energetic consequences of nitrite stress in Desulfovibrio vulgaris Hildenborough, inferred from global transcriptional analysis

Desulfovibrio vulgaris Hildenborough was used as a model organism to study stress response to nitrite, an important intermediate in nitrogen cycle in order to understand the metabolism of microorganisms under adverse environmental conditions for improved bioremediation efforts. Global trnscription profiling with whole-genome microarays revealed coordinated cascades of responses to nitrite in pathways of energy metabolism, nitrogen metabolism, oxidative stress response and iron homeostasis.