Back to Search Start Over

Photoinduced reductive repair of thymine glycol: Implications for excess electron transfer through DNA containing modified bases

Authors :
Ito, Takeo
Kondo, Akiko
Terada, Satoru
Nishimoto, Sei-Ichi
Source :
Journal of the American Chemical Society. August 23, 2006, Vol. 128 Issue 33, p10934, 9 p.
Publication Year :
2006

Abstract

An investigation of the redox reactivity of thymine glycol lesions in DNA and influence of such a base modification on the efficiency of excess electron transfer (EET) through the duplex DNA is described. The findings reveal the prospect of reductive repair of thymine glycol in DNA and implications of DNA mediated EET with respect to DNA base damage reactions.

Details

Language :
English
ISSN :
00027863
Volume :
128
Issue :
33
Database :
Gale General OneFile
Journal :
Journal of the American Chemical Society
Publication Type :
Academic Journal
Accession number :
edsgcl.152901622