Phagocytosis by pig alveolar macrophages of actinobacillus pleuropneumoniae serotype 2 mutant strains defective in haemolysin II (ApxII) and pelurotoxin (ApxIII)

Authors :: Cullen, Janice M.
Rycroft, Andrew N.
Source :: Microbiology. Feb, 1994, Vol. 140 Issue 2, p237, 8 p.
Publication Year :: 1994
Abstract: A study of pig alveolar macrophages reveals that the macrophages phagocytose Actinobacillus pleuropneumoniae HK 361 only in the presence of convalescent pig serum and absence of haemolysin II (ApxII) and pleurotoxin (ApxIII). Combination with ApxII exhibits extreme toxicity that the immune serum is unable to neutralize. The mutant form incubator with convalescent pig serum yields undamaged macrophages.

Subjects :: Macrophages -- Research
Phagocytosis -- Research
Biological sciences

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