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Multiple deprotonations and deamination of phenethylamines to synthesize pyrroles

Authors :
Xiaobing Wan
Dong Xing
Zhao Fang
Bijie Li
Fei Zhao
Keya Zhang
Liping Yang
Zhangjie Shi
Source :
Journal of the American Chemical Society. Sept 20, 2006, Vol. 128 Issue 37, p12046, 2 p.
Publication Year :
2006

Abstract

A unique process is presented in which two different [sp.sup.3] C-H bonds are selectively activated under the same conditions to construct polysubstituted pyrroles from commercially available phenethylamines. During the transformation, twelve protons and two nitrogen atoms are removed, at least twelve bonds are cleaved and five new bonds are constructed in one pot.

Details

Language :
English
ISSN :
00027863
Volume :
128
Issue :
37
Database :
Gale General OneFile
Journal :
Journal of the American Chemical Society
Publication Type :
Academic Journal
Accession number :
edsgcl.153428902