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Therapeutic hypercapnia prevents chronic hypoxia-induced pulmonary hypertension in the newborn rat
- Source :
- The American Journal of Physiology. Nov, 2006, Vol. 291 Issue 5, pL912, 11 p.
- Publication Year :
- 2006
-
Abstract
- Induction of hypercapnia by breathing high concentrations of carbon dioxide (C[O.sub.2]) may have beneficial effects on the pulmonary circulation. We tested the hypothesis that exposure to C[O.sub.2] would protect against chronic pulmonary hypertension in newborn rats. Atmospheric C[O.sub.2] was maintained at carbon dioxide; endothefin; oxidant stress; 8-isoprostane; echocardiography
Details
- Language :
- English
- ISSN :
- 00029513
- Volume :
- 291
- Issue :
- 5
- Database :
- Gale General OneFile
- Journal :
- The American Journal of Physiology
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.155292554