TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling

Authors :: Kuwahara, Koichiro
Wang, Yanggan
McAnally, John
Richardson, James A.
Bassel-Duby, Rhonda
Hill, Joseph A.
Olson, Eric N.
Source :: Journal of Clinical Investigation. Dec, 2006, Vol. 116 Issue 12, p3114, 13 p.
Publication Year :: 2006
Abstract: The heart responds to injury and chronic pressure overload by pathologic growth and remodeling, which frequently result in heart failure and sudden death. Calcium-dependent signaling pathways promote cardiac growth and [...]

Subjects :: Gene expression -- Research
T cell proliferation -- Research
T cell proliferation -- Health aspects
Heart failure -- Research

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