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calmodulin-dependent protein kinase II regulates cardiac [Na.sup.+] channels
- Source :
- Journal of Clinical Investigation. December 2006, Vol. 116 Issue 12, p3127, 12 p.
- Publication Year :
- 2006
-
Abstract
- In heart failure (HF), [Ca.sup.2+]/calmodulin kinase II (CaMKII) expression is increased. Altered [Na.sup.+] channel gating is linked to and may promote ventricular tachyarrhythmias (VTs) in HF. Calmodulin regulates [Na.sup.+] channel [...]
Details
- Language :
- English
- ISSN :
- 00219738
- Volume :
- 116
- Issue :
- 12
- Database :
- Gale General OneFile
- Journal :
- Journal of Clinical Investigation
- Publication Type :
- Academic Journal
- Accession number :
- edsgcl.156144241