Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL

Authors :: Vaisar, Tomas
Pennathur, Subramaniam
Green, Pattie S.
Gharib, Sina A.
Hoofnagle, Andrew N.
Cheung, Marian C.
Byun, Jaeman
Vuletic, Simona
Kassim, Sean
Singh, Pragya
Chea, Helen
Knopp, Robert H.
Brunzell, John
Geary, Randolph
Chait, Alan
Zhao, Xue-Qiao
Elkon, Keith
Marcovina, Santica
Ridker, Paul
Oram, John F.
Heinecke, Jay W.
Source :: Journal of Clinical Investigation. March, 2007, Vol. 117 Issue 3, p746, 11 p.
Publication Year :: 2007
Abstract: HDL lowers the risk for atherosclerotic cardiovascular disease by promoting cholesterol efflux from macrophage foam cells. However, other antiatherosclerotic properties of HDL are poorly understood. To test the hypothesis that [...]

Subjects :: Anti-inflammatory drugs -- Health aspects
Anti-inflammatory drugs -- Research
Cholesterol -- Health aspects
Cholesterol -- Research
Molecular biology -- Research
Protease inhibitors -- Research
Proteomics -- Research

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