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Intestinal capsaicin transiently attenuates suppression of sham feeding by oleate

Authors :
Tamura, Connie S.
Ritter, Robert C.
Source :
The American Journal of Physiology. August, 1994, Vol. 267 Issue 2, pR561, 8 p.
Publication Year :
1994

Abstract

Studies of the influence of capsaicin on intraintestinal oleate-induced reduction in sham feeding reveal that intestinal infusion of capsaicin reversibly attenuates the suppression of sham feeding by oleic acid. Intraintestinal oleate acts through capsaicin-sensitive vagal sensory neurons which act as a neural substrate for mediating the oleate suppression of sham-feeding. Capsaicin temporarily incapacitates the capsaicin-sensitive substrate but does not impair cholecystokinin-induced reduction of feeding or damage to the viscerosensory neurons.

Details

ISSN :
00029513
Volume :
267
Issue :
2
Database :
Gale General OneFile
Journal :
The American Journal of Physiology
Publication Type :
Academic Journal
Accession number :
edsgcl.16150755