Reduced neuron-specific expression of the TAF1 gene is associated with X-linked dystonia-parkinsonism

Various studies are performed to reveal the disease-causative gene of X-linked dystonia-parkinsonism (XDP). The genome sequencing analysis and expression analysis have shown that the reduced neuron-specific expression of the TATA-binding protein-associated factor 1 gene (TAF1) is associated with XDP.